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Listar por autor "Tabares, Lucía"
Mostrando ítems 1-20 de 47
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Artículo
Active zones and the readily releasable pool of synaptic vesicles at the neuromuscular junction of the mouse
Ruiz Laza, Rocío; Cano, Raquel; Casañas, Juan José; Gaffield, Michael A.; Betz, William J.; Tabares, Lucía (SOC NEUROSCIENCE, 2011-02-09)Synchronous neurotransmitter releaseis a highly regulated processthattakes place at specializations atthe presynapticmembrane ...
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Altered Intracellular Ca2+ Homeostasis in Nerve Terminals of Severe Spinal Muscular Atrophy Mice
Ruiz Laza, Rocío; Casañas, Juan José; Torres-Benito, Laura; Cano, Raquel; Tabares, Lucía (SOC NEUROSCIENCE, 2010)Low levels of survival motor neuron (SMN) protein result in spinal muscular atrophy (SMA), a severe genetic disease ...
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BDNF is a mediator of glycolytic fiber-type specification in mouse skeletal muscle
Delezie, Julien; Weihrauch, Martin; Maier, Geraldine; Tejero, Rocío; Ham, Daniel J.; Gill, Jonathan F.; Tabares, Lucía; Handschin, Christoph (NATL ACAD SCIENCES, 2019-07-18)Brain-derived neurotrophic factor (BDNF) influences the differentiation, plasticity, and survival of central neurons and ...
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Calcium is reduced in presynaptic mitochondria of motor nerve terminals during neurotransmission in SMA mice
López Manzaneda, Mario; Franco Espín, Julio; Tejero Navarro, Rocío; Cano, Raquel; Tabares, Lucía (Oxford University Press, 2021-04-15)Spinal muscular atrophy (SMA) is an autosomal recessive degenerative motor neuron disease characterized by symmetrical ...
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Artículo
Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction
Bertone, Nicolas Ivan; Groisman, Ayelén Ivana; Mazzone, Graciela Lujan; Cano, Raquel; Tabares, Lucía; Uchitel, Osvaldo Daniel (Wiley, 2017)Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic ...
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Artículo
Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy
Simon, Christian M.; Jablonka, Sibylle; Ruiz Laza, Rocío; Tabares, Lucía; Sendtner, Michael (OXFORD UNIV PRESS, 2010)Proximal spinal muscular atrophy (SMA) is caused by homozygous loss or mutation of the SMN1 gene on human chromosome 5. ...
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Artículo
CSP alpha-deficiency causes massive and rapid photoreceptor degeneration
Schmitz, Frank; Tabares, Lucía; Khimich, Darina; Strenzke, Nicola; Villa Polo, Pedro de la; Castellano Muñoz, Manuel; Bulankina, Anna; Moser, Tobias; Fernández-Chacón, Rafael; Südhof, Thomas C. (2006)Cysteine string protein (CSP) _ is an abundant synaptic vesicle protein that contains a DNA-J domain characteristic of ...
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Artículo
CSPα, a molecular co-chaperone essential for short and long-term synaptic maintenance
López Ortega, Elena; Ruiz Laza, Rocío; Tabares, Lucía (Frontiers Media S.A., 2017-02-10)Cysteine string protein a (CSPα) is a vesicle protein located in the presynaptic terminal of most synapses. CSPα is an ...
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Artículo
Cysteine string protein-α is essential for the high calciumsensitivity of exocytosis in a vertebrate synapse
Ruiz Laza, Rocío; Casañas, J. J.; Südhof, T. C.; Tabares, Lucía (Wiley, 2008)Cysteine string protein (CSPa) is a synaptic vesicle protein present in most central and peripheral nervous system ...
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Tesis Doctoral
Different Modes of Synaptic Vesicle Recycling un Synaptophysin-pHluorin Transgenic Mouse Motor Nerve Terminals
Cano García, Raquel (2014)In the present work, a new tool for studying synaptic vesicle exo- and end ... The adult vertebrate NMJ is a highly reliable ...
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Artículo
Dopamine induces intracellular Ca2+ signals mediated by alpha(1B)-adrenoceptors in rat pineal cells
Rey, Elkin; Hernández-Díaz, Francisco J.; Abreu, Pedro; Alonso, Rafael; Tabares, Lucía (ELSEVIER SCIENCE BV, 2001)We have studied the functional interaction of dopamine with a -adrenoceptor subtypes by measuring intracellular Ca2q 1 ...
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Artículo
Editorial: Molecular nanomachines of the presynaptic terminal
Rizzoli, Silvio O.; Tabares, Lucía (Frontiers Research Foundation, 2016) -
Artículo
Editorial: Molecular Nanomachines of the Presynaptic Terminal, Volume II
Tabares, Lucía; Rizzoli, Silvio O. (Frontiers Research Foundation, 2022)The synapse has been designed and refined during animal evolution for two main processes: (1) to translate and transmit ...
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Artículo
Effects of membrane depolarization and divalent-cations on anaphylactic histamine secretion
Pintado, E.; Dorado, M.E.; Tabares, Lucía; López Barneo, José (1986)The effects of membrane depolariz.ation and divalent cations on histamine release have been studied in sensitized mast ...
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Tesis Doctoral
Electrofisiología de células adrenocorticales: Estudio mediante el registro intracelular y la técnica de “patch clamp”
Tabares, Lucía (1985-12-16)El presente trabajo se centra en el estudio de las características electrofisiológicas de células adrenocorticales en ...
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Tesis Doctoral
Estudio de la señal de calcio y las corrientes iónicas en el acoplamiento entre el estímulo y la secreción en células pineales en la rata
Marín Caballos, Antonio Jesús (1995-06-23)Se han empleado distintas técnicas para estudiar los mecanismos implicados en las diferentes etapas del proceso de ...
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Tesis Doctoral
Estudio del calcio mitocondrial en terminales nerviosos motores y su relación en el proceso de neurotransmisión. Alteraciones en la atrofia muscular espinal
López Manzaneda, Mario (2019-11-07)La mitocondria es uno de los principales moduladores de los niveles de calcio citosólico además de la principal fuente de ...
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Artículo
Exocytosis of catecholamine (CA)-containing and CA-free granules in chromaffin cells
Tabares, Lucía; Alés González de la Higuera, Eva María; Lindau, Manfred; Álvarez de Toledo Naranjo, Guillermo (Science Direct, 2001-08-27)Recent evidence suggests that endocytosis in neuroendocrine cells and neurons can be tightly coupled to exocytosis, ...
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Artículo
Fast motor axon loss in SMARD1 does not correspond to morphological and functional alterations of the NMJ
Krieger, Frank; Elflein, Nicole; Ruiz Laza, Rocío; Guerra, Joana; Serrano, Antonio L.; Asan, Esther; Tabares, Lucía; Jablonka, Sibylle (Elsevier, 2013-06)Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a childhood motoneuron disease caused by mutations ...
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Tesis Doctoral
Función de la proteína de supervivencia de motoneuronas (SMN) en la maduración funcional y organización sináptica en un modelo murino de atrofia muscular espinal
Torres Benito, Laura (2012-11-23)La Atrofia Muscular Espinal (AME) es una enfermedad autosómica recesiva caracterizada por debilidad muscular y deterioro ...